Alzheimer-forum opiekunów

Póki co po angielsku ale temat warty bliższego poznania, bo podejrzewam, że zwykli lekarze skupiają się wyłącznie na standardowych przypadkach:

Najpierw spis treści na stronie 43 dokumentu:

http://ec.europa.eu/health/archive/ph_t ... ias_en.pdf

NEURO-DEGENERATIVE DISEASES 5

1. FAMILIAL ALZHEIMER DISEASE (FAD) BY GIULIANO BINETTI 6
2. LEWY BODY DISEASES BY CLIVE EVERS 9
2.1. DEMENTIA WITH LEWY BODIES (DLB) 9
2.2. DEMENTIA IN PARKINSON’S DISEASE (PDD) BY KURT JELLINGER 12
3. FRONTO-TEMPORAL DEGENERATION (FTD) BY ANDRÉ DELACOURTE 14
- 3.1. CLINICAL MANIFESTATION 15
-- 3.1.1. Fronto-temporal dementia (FTD) by André Delacourte 15
-- 3.1.2. Primary Progressive Aphasia (PPA) by André Delacourte 18
-- 3.1.3. Semantic Dementia (SD) by André Delacourte 20
- 3.2. HISTOPATHOLOGICAL SUB-TYPES 22
-- 3.2.1. FTD with parkinsonism linked to chromosome 17 (FTDP-17) by André Delacourte 22
-- 3.2.2. Pick’s disease (PiD) by André Delacourte 24
-- 3.2.3. Dementia lacking distinctive histology (DLDH) 26
4. PROGRESSIVE SUPRANUCLEAR PALSY (PSP) BY ANDRÉ DELACOURTE 28
5. CORTICOBASAL DEGENERATION (CBD) BY ANDRÉ DELACOURTE 31
6. ARGYROPHILIC GRAIN DISEASE (AGD) BY ANDRÉ DELACOURTE & KURT JELLINGER 33
7. MULTIPLE SYSTEM ATROPHY (MSA) BY ANDRÉ DELACOURTE 35
8. AMYOTROPHIC LATERAL SCLEROSIS (ALS) BY GIULIANO BINETTI 37
9. ATAXIAS BY GIULIANO BINETTI 41
10. HUNTINGTON’S DISEASE (HD) BY GIULIANO BINETTI 44
11. DOWN SYNDROME BY JOS VAN DER POEL 47
12. FAMILIAL BRITISH DEMENTIA BY ANDRÉ DELACOURTE 49

INFECTIOUS DISEASES 51

13.1. SPORADIC CJD BY ANDRÉ DELACOURTE AND CLIVE EVERS 54
13.2. TRANSMISSIBLE CJD 57
13.2.1. Iatrogenic CJD by André Delacourte and Clive Evers 57
13.2.2. Variant CJD (vCJD) by André Delacourte and Clive Evers 60
13.3. FAMILIAL CJD BY ANDRÉ DELACOURTE AND CLIVE EVERS 63
13.4. FATAL FAMILIAL INSOMNIA (FFI) BY ANDRÉ DELACOURTE 65
13.5. GERSTMANN-STRAUSSLER-SCHEINKER DISEASE BY ANDRÉ DELACOURTE 67
13. AIDS DEMENTIA COMPLEX (ADC) BY JOS VAN DER POEL 69
14. SYPHILIS BY ALEXANDER KURZ 71
15. POSTENCEPHALITIC PARKINSONISM (PEP) BY KURT JELLINGER 74
16. HERPES ENCEPHALITIS BY KURT JELLINGER 76

METABOLIC DISEASES 78

17. THYROID DISORDERS BY CLIVE EVERS 79
18. NEURO-DEGENERATION WITH BRAIN IRON ACCUMULATION TYPE I (NBIA 1) BY KURT JELLINGER 82
19. CEREBRAL LIPIDOSES BY ALEXANDER KURZ 84
20.1. TAY-SACHS DISEASE (TSD) BY ALEXANDER KURZ 84
20.2. SANDHOFF DISEASE BY ALEXANDER KURZ 86
20.3. GAUCHER DISEASE BY ALEXANDER KURZ 88
20.4. NIEMANN-PICK DISEASE (NPD) BY ALEXANDER KURZ 90
20.5. KRABBE DISEASE BY ALEXANDER KURZ 92
20.6. NEURONAL CEROID LIPOFUSCINOSES (NCL) BY ALEXANDER KURZ 94
20.7. CEREBROTENDINOUS XANTHOMATOSIS (CTX) BY ALEXANDER KURZ 96
20. DEMENTIA IN HEPATIC AND RENAL FAILURE BY KURT JELLINGER 98
21. DEMENTIA DUE TO CHRONIC HYPOVITAMINOSIS BY KURT JELLINGER 100
22. METACHROMATIC LEUKODYSTROPHY (MLD) BY ALEXANDER KURZ 102
23. ADRENOLEUKODYSTROPHY (ALD) BY ALEXANDER KURZ 104

TRAUMATIC DISEASES 106

24. REPEATED HEAD TRAUMA BY ALEXANDER KURZ 107

TOXIC DISEASES 109

25. WERNICKE-KORSAKOFF SYNDROME (WKS) BY CLIVE EVERS 110

CEREBRO-VASCULAR DEMENTIA 113

26. CADASIL BY KURT JELLINGER 114
27. BINSWANGER DISEASE BY JOS VAN DER POEL 115
28. CEREBRAL AMYLOID ANGIOPATHY (CAA) BY KURT JELLINGER 116

OTHER RARE CAUSES OF DEMENTIA 117

29. COGNITIVE DYSFUNCTION IN MULTIPLE SCLEROSIS BY CLIVE EVERS 118
30. NORMAL PRESSURE HYDROCEPHALUS (NPH) BY JOS VAN DER POEL 121

Kolejna publikacja:

http://apt.rcpsych.org/content/15/5/364.full.pdf

Degenerative causes of dementia

Familial Alzheimer’s disease
Pure hippocampal sclerosis
Frontotemporal lobar degeneration
Primary progressive (non-fluent) aphasia
Semantic dementia
Progressive supranuclear palsy (Steele–Richardson–Olszewsky syndrome)
Corticobasal degeneration
Multiple system atrophy (Shy–Drager syndrome)
Amyotrophic lateral sclerosis/motor neuron disease (Lou Gehrig’s disease)
Huntington’s disease
Spinocerebellar and Friedreich’s ataxias
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (Nasu–Hakola disease)

Vascular causes of dementia

Multi-infarct dementia
Single-infarct (post-stroke) dementia
Subcortical dementia
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
Binswanger’s disease
Cerebral amyloid angiopathy

Human prion diseases that cause dementia

Creutzfeldt–Jakob disease
- sporadic
- iatrogenic
- variant
- familial
Fatal familial insomnia
Gerstmann–Straussler–Scheinker disease

Infective causes of dementia

Endoparasitic infections
Lyme disease
Neurosyphilis
Cerebral toxocariasis
Neurocysticerosis
Whipple’s disease
Viral infections
Viral meningitis
HIV-related dementia (AIDS dementia complex)
Progressive multifocal leukoencephalopathy
Subacute sclerosing panencephalitis
Bacterial infections
Tuberculous meningitis
Meningococcal meningitis
Fungal infections
Cryptococcal meningitis

Immunologically Mediated Dementias
Michael H. Rosenbloom, MD, Sallie Smith, MD, Gulden Akdal, MD, and Michael D. Geschwind, MD, PhD

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832614/


Immune-Mediated Dementia/Encephalopathy Associated With Specific Antigens or Antibodies

Paraneoplastic syndromes

Anti-Hu antibody
Anti-CV2 antibody
Anti-Ma2 antibody
Anti-NMDAR antibody
Anti-AMPAR antibody
Anti-Ri antibodies

Nonparaneoplastic syndromes

Anti–voltage-gated potassium channel encephalopathy
Hashimoto's encephalopathy
Anti–glutamic acid decarboxylase antibody syndrome
Gluten-sensitivity dementia
Sjögren's encephalopathy
Systemic lupus erythematosus

Immune-Mediated Dementia/Encephalopathy Not Associated With Specif c Antigens or Antibodies

Sarcoidosis
Behçet's disease
Primary angiitis of the CNS

Paraneoplastic antibodies or syndromes associated with cognitive impairment

http://www.ncbi.nlm.nih.gov/pmc/article ... /table/T1/

Diagnostic workup of immune-mediated dementias

http://www.ncbi.nlm.nih.gov/pmc/article ... /table/T2/

a także

THE AUTOIMMUNE ENCEPHALOPATHIES
Pridmore S. Download of Psychiatry, Chapter 36. Last modified: July, 2012

http://eprints.utas.edu.au/287/43/Chapt ... athies.pdf

Limbic encephalitis (Classical paraneoplastic encephalitidies)
Recently described encephalitidies
Anti-NMDA receptor encephalitis
Anti-AMPA receptor encephalitis
Anti-GABAB Receptor Encephalitis
Anti-Voltage-gated potassium channel disorders
Effects of maternal antibodies on fetal development
Schizophrenia

Neurological syndromes which can be mistaken for psychiatric conditions
C Butler, A Z J Zeman
J Neurol Neurosurg Psychiatry 2005;76:i31-i38 doi:10.1136/jnnp.2004.060459

http://jnnp.bmj.com/content/76/suppl_1/i31.full

MAJOR CATEGORIES OF NEUROLOGICAL DISORDER AND THEIR PSYCHIATRIC PRESENTATIONS
INHERITED DISORDERS
ACQUIRED DISORDERS
- Neurodegenerative disorders
- Vascular disorders
- Inflammatory and infective disorders
- Neoplastic and paraneoplastic
- Trauma
- Metabolic/endocrine
- Deficiency disorders
- Structural disorders
UNUSUAL NEUROLOGICAL SYNDROMES THAT MAY PRESENT AS PSYCHIATRIC
- Consciousness
- Narcolepsy
- REM sleep behaviour disorder
- Attention
- Balint’s syndrome
- Executive function
- Memory
-- Transient global amnesia
-- Transient memory disturbances in temporal lobe epilepsy
-- Reduplicative paramnesia
- Perception
-- Charles Bonnet syndrome
-- Peduncular hallucinosis
- Misidentification syndromes
-- Capgras delusion
-- Frégoli delusion
- Language
- Praxis
-- Alien hand syndrome
- Mood and emotion
- Thought
- Behaviour and personality

Kolejne do listy:

- nadmiar amoniaku (spowodowane np. złym stanem wątroby lub niedoborem jednego z enzymów).

Właśnie odkryłem prawdziwą skarbnicę wiedzy:

Rzadkie choroby według kategorii:
http://rarediseases.info.nih.gov/gard/categories

M.in.:
- Behavioral and mental disorders
- Nervous System Diseases.